If you are experiencing extreme pain in your big toe that keeps you up at night and experience joint pain coming from it, it could be a sign of gout. Gout comes from needle-like crystals formed in the joints, usually around the feet and ankles, due to excess uric acid in the body. Fortunately, a change in diet and weight loss can help treat symptoms. For more about gout and gout treatment, click here:: Sudden, severe joint pain at night? It could be gout.